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2023
Journal article
Evidence for Natural Products as Alternative Wound-Healing Therapies.
Chronic, non-healing wounds represent a significant area of unmet medical need and are a growing problem for healthcare systems around the world. They affect the quality of life for patients and are an economic burden, being difficult and time consuming to treat. They are an escalating problem across the developed... -
2020
Journal article
Evaluation of Cypholophus macrocephalus sap as a treatment for infected cutaneous ulcers in Papua New Guinea.
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2020
Journal article
Lepiniopsis ternatensis sap stimulates fibroblast proliferation and down regulates macrophage TNF-α secretion
The sap of the tree Lepiniopsis ternatensis is used as a topical treatment for cutaneous leg ulcers in Papua New Guinea. This study, which is the first investigation of this medicinal plant, examines the effect of the sap on wound healing biology using human-derived primary cell lines. NMR spectra from...Moses, Rachael L. ; Dally, Jordanna ; Lundy, Fionnuala T. ; Langat, Moses K. ; Kiapranis, Robert …
fibroblast, Lepiniopsis ternatensis, trifucol, TNF-α, Papua New Guinea, and wound healing