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  5. Comparative metabolite profiling of three savannic species of Banisteriopsis (Malpighiaceae) via UPLC‐MS/MS and chemometric tools.

Comparative metabolite profiling of three savannic species of Banisteriopsis (Malpighiaceae) via UPLC‐MS/MS and chemometric tools.

Resource type
Journal article
Creator (person)
Guimarães da Silva, Jaqueline Munise
ORCIDORCID logo
de Almeida, Rafael Felipe
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Zeraik, Maria Luiza
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Date published
May 31, 2024
Abstract
Banisteriopsis (Malpighiaceae) is an important genus of neotropical savannas with related biological and medicinal activities but under‐explored metabolomic profiles. We present a chemometric analysis for discriminating secondary metabolites of three species of Banisteriopsis (B. laevifolia, B. malifolia, and B. stellaris) leaves. Initially, each species was separately extracted with ethanol:water (4:1, v/v) and analysed by Ultra Performance Liquid Chromatography coupled with Mass Spectrometry (UPLC‐MS/MS). The chromatographic profiles were subjected to Global Natural Product Social (GNPS) and Partial Least Squares Discriminant Analysis (PLS‐DA). Eighty‐nine compounds (cosine ≥ 0.90) were annotated, including flavonoids, phenolics, and acids. The chemometric analysis (VIP Score) showed each species' relative concentration of the more relevant compounds. In addition, four compounds that discriminate the metabolomic profiles of B. laevifolia, B. malifolia, and B. stellaris were identified by PLS‐DA.
Funder
Funder nameAwards
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Brazil
Conselho Nacional de Desenvolvimento Científico e Tecnológico, Brazil
Journal title
Chemistry & Biodiversity
Article number
e202400679
Publisher
Wiley-VCH GmbH
Place of publication
Weinheim, Germany
ISSN
1612-1872
eISSN
1612-1880
Date accepted
May 31, 2024
Official URL
https://doi.org/10.1002/cbdv.202400679
Rights statement
In Copyright
DOI
10.1002/cbdv.202400679
Keywords
Banisteriopsis
Metabolite profiling
Banisteriopsis laevifolia
Metabolomic Analysis
Banisteriopsis stellaris
Savannic species
Multivariate analysis
Banisteriopsis. malifolia
Additional information
IF = 2.745 (2023-2024)
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