Review of Recent Medicinal Applications of Rhenium(I) Tricarbonyl Complexes.
Name
ijms-26-07005-v2.pdf
Description
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Size
1.33 MB
Format
Adobe PDF
Checksum (CRC64NVME)
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Resource type
Date published
July 21, 2025
Abstract
The use of metal-based complexes is currently taking centre stage in the field of nanomedicine for the treatment and control of various ailments. Rhenium(I) tricarbonyl complexes have frequently been evaluated in vitro for their anticancer activities, and a few have advanced to in vivo and clinical trials, owing to the distinct application characteristics of these complexes. Their inception in drug development is key. This study explores a detailed chronological overview of the medical applications of Re(I) tricarbonyl complexes over the past six years (2019–2024), focusing on their applications and clinical tests in the control and management of various ailments. An in-depth examination of their activities in anticancer treatments, Chagas disease, antifungal infections, antimalarial, and microbial infections was conducted, comparing the complexes to various standard antibiotics, conventional antimalarial drugs, antifungals, and standard anticancer agents.
Project(s)
Priority 2: Trait Diversity and Function
Funder
| Funder name | Awards |
National Research Fund, South Africa | PMDS23041793997 - Grant No. 129468 |
Tshwane University of Technology, South Africa | Article Processing Charge |
Journal title
International Journal of Molecular Sciences
Volume
26
Issue
14
Article number
7005
Publisher
MDPI AG
Place of publication
Basel, Switzerland
eISSN
1422-0067
Date accepted
July 15, 2025
Official URL
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Rights statement
In Copyright
Additional information
IF = 4.9 (2024)