Journal article

Lipid metabolism is dysregulated in a mouse model of diabetes.

Public Deposited

Creator
  • Furse, Samuel  ( ORCID   ISNI )
2022

Abstract
  • Much evidence for diabetes mellitus being associated with dysregulated lipid metabolism has been accrued from studies using blood plasma. However, the systemic dysregulation these results point to is not understood. This study used Lipid Traffic Analysis on data from a mouse model of diabetes to test the hypothesis that the systemic control of lipid metabolism differed in a model of diabetes. This provided eidence for changes in the systemic control of both triglyceride and phospholipid metabolism that were not attributable to dietary intake. This supports the conclusion that diabetes is a systemic condition associated with dysregulated lipid metabolism through several pathways.

Items:

Thumbnail File Name Date Uploaded Visibility File Size Actions
s11306-022-01884-w.pdf 2022-11-29 Public 670 KB

Metadata

Resource Type
  • Journal article
Creator
  • Furse, Samuel  ( ORCID   ISNI )
Date published
  • 2022-06
Institution
  • Royal Botanic Gardens, Kew
Organisational unit
  • Science
Project name
  • Priority 2: Trait Diversity and Function
Funder
  • Name: Biotechnology and Biological Sciences Research Council, United Kingdom 
  • Awards: BB/M027252/1 | BB/T014210/1
Journal title
  • Metabolomics
Volume
  • 18
Article number
  • 36
Publisher
  • Springer Science and Business Media LLC
Place of publication
  • Berlin/Heidelberg, Germany
eISSN
  • 1573-3890
Date accepted
  • 2022-04-01
Official URL
Licence
  • CC BY 4.0 Attribution
Rights statement
DOI
  • 10.1007/s11306-022-01884-w
Alternate identifier
  • identifier: 36 
  • type: article-number
Keyword
Additional Information
  • IF = 4.29 (2021-2022)