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2022
Journal article
Cytotoxicity of Fenugreek Sprout and Seed Extracts and Their Bioactive Constituents on MCF-7 Breast Cancer Cells.
Trigonella foenum-graecum L. (fenugreek), a member of the legume family (Fabaceae), is a promising source of bioactive phytochemicals, which explains its traditional use for a variety of metabolic disorders including cancer. The current study aimed to evaluate extracts of fenugreek seeds and sprouts, and some of their constituents, to compare...Khoja, Kholoud K. ; Howes, Melanie-Jayne R. ; Hider, Robert ; Sharp, Paul A. ; Farrell, Iain W. …
Cytotoxicity, Fenugreek, MCF-7, Trigonella foenum-graecum, Cancer, and Iron
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2020
Journal article
The Pathopharmacological Interplay between Vanadium and Iron in Parkinson’s Disease Models.
Parkinson’s disease (PD) pathology is characterised by distinct types of cellular defects, notably associated with oxidative damage and mitochondria dysfunction, leading to the selective loss of dopaminergic neurons in the brain’s substantia nigra pars compacta (SNpc). Exposure to some environmental toxicants and heavy metals has been associated with PD pathogenesis....Ohiomokhare, Samuel ; Olaolorun, Francis ; Ladagu, Amany ; Olopade, Funmilayo ; Howes, Melanie-Jayne R. …
Oxidative stress, Vanadium, RONS, Parkinson’s, Mitochondria, Iron, and Motor activity