Search Constraints
Search Results
-
2022
Journal article
Anti-HIV crotocascarin ω from Kenyan Croton dichogamus.
-
2022
Journal article
Anti-HIV Ermiasolides from Croton megalocarpus.
In recent years, elucidation of novel anti-HIV bioactive compounds from natural products is gaining importance rapidly, not only from the research and publications, but also from controlled clinical studies. Here we report three new anti-HIV eudesmane-type sesquiterpenes, 5β-Hydroxy-8α-methoxy eudesm-7(11)-en-12,8-olide (1), 5β,8α-Dihydroxy eudesm-7(11)-en-12,8-olide (2) and 5β-Hydroxy-8H-β-eudesm-7(11)-en-12,8-olide (3). These are trivially named...Terefe, Ermias Mergia ; Okalebo, Faith Apolot ; Derese, Solomon ; Langat, Moses K. ; Mas-Claret, Eduard …
Ermiasolides, Cytotoxicity, Anti-HIV activity, HIV-1, and Croton megalocarpus
-
2022
Journal article
In vitro anti-HIV and cytotoxic effects of pure compounds isolated from Croton macrostachyus Hochst. Ex Delile.
is an important plant in traditional African medicine, widely utilized to treat a variety of diseases. In Kenya, HIV-infected patients use leaf and root decoctions of the plant as a cure for cough, back pain, bleeding, skin diseases, warts, pneumonia, and wounds. This study aimed to evaluate the anti-HIV activities...