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2018
Journal article
Volatile Terpenes and Brain Function: Investigation of the Cognitive and Mood Effects of Mentha × Piperita L. Essential Oil with In Vitro Properties Relevant to Central Nervous System Function.
Background: Extracts of several members of the monoterpene-rich Lamiaceae sub-family Nepetoideae, including those from the Salvia (sage), Melissa (Lemon balm) and Rosmarinus (rosemary) genera, evince cognitive and mood effects in humans that are potentially related to their effects on cholinergic and GABAergic neurotransmission. To date, despite promising in vitro properties,...Kennedy, David ; Okello, Edward ; Chazot, Paul ; Howes, Melanie-Jayne ; Ohiomokhare, Samuel …
Mentha, Terpenes, Mint, Brain function, and Cognition
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2020
Journal article
The Pathopharmacological Interplay between Vanadium and Iron in Parkinson’s Disease Models.
Parkinson’s disease (PD) pathology is characterised by distinct types of cellular defects, notably associated with oxidative damage and mitochondria dysfunction, leading to the selective loss of dopaminergic neurons in the brain’s substantia nigra pars compacta (SNpc). Exposure to some environmental toxicants and heavy metals has been associated with PD pathogenesis....Ohiomokhare, Samuel ; Olaolorun, Francis ; Ladagu, Amany ; Olopade, Funmilayo ; Howes, Melanie-Jayne R. …
Oxidative stress, Vanadium, RONS, Parkinson’s, Mitochondria, Iron, and Motor activity