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2023
Journal article
Fungal Drug Discovery for Chronic Disease: History, New Discoveries and New Approaches.
Fungal-derived drugs include some of the most important medicines ever discovered, and have proved pivotal in treating chronic diseases. Not only have they saved millions of lives, but they have in some cases changed perceptions of what is medically possible. However, now the low-hanging fruit have been discovered it has...Prescott, Thomas A. K. ; Hill, Rowena ; Mas-Claret, Eduard ; Gaya, Ester ; Burns, Edie
Drugs, Self-resistance, Mechanism of action, Drug distribution, Ecological function, and Fungi
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2023
Journal article
First Whole Genome Sequence and Flow Cytometry Genome Size Data for the Lichen-Forming Fungus Ramalina farinacea (Ascomycota).
Lichen-forming fungi are a diverse and ecologically important group of obligate mutualistic symbionts. Due to difficulties with maintaining them in culture and their extremely slow growth, lichenologists are increasingly opting for metagenomic sequencing followed by symbiont genome separation using bioinformatic pipelines. However, without knowing the true genome size of the...Llewellyn, Theo ; Mian, Sahr ; Hill, Rowena ; Leitch, Ilia J ; Gaya, Ester
Lichen, Genome size, Ramalina farinacea, Symbiosis, Ramalinaceae, Long-read sequencing, and Metagenomics
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2023
Journal article
Tapping culture collections for fungal endophytes: first genome assemblies for three genera and five species in the Ascomycota.
The Ascomycota form the largest phylum in the fungal kingdom and show a wide diversity of lifestyles, some involving associations with plants. Genomic data is available for many ascomycetes that are pathogenic to plants, but endophytes, which are asymptomatic inhabitants of plants, are relatively understudied. Here, using short- and long-read...Hill, Rowena ; Levicky, Quentin ; Pitsillides, Frances ; Junnonen, Amy ; Arrigoni, Elena …
Cytometric completeness, Ascomycota, Culture collections, and Fungal endophytes
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2022
Journal article
Madagascar’s extraordinary biodiversity: Threats and opportunities.
Madagascar’s unique biota is heavily affected by human activity and is under intense threat. Here, we review the current state of knowledge on the conservation status of Madagascar’s terrestrial and freshwater biodiversity by presenting data and analyses on documented and predicted species-level conservation statuses, the most prevalent and relevant threats,... -
2022
Journal article
Madagascar’s extraordinary biodiversity: Evolution, distribution, and use.
Madagascar’s biota is hyperdiverse and includes exceptional levels of endemicity. We review the current state of knowledge on Madagascar’s past and current terrestrial and freshwater biodiversity by compiling and presenting comprehensive data on species diversity, endemism, and rates of species description and human uses, in addition to presenting an updated... -
2021
Journal article
Seed Banks as Incidental Fungi Banks: Fungal Endophyte Diversity in Stored Seeds of Banana Wild Relatives.
Hill, Rowena ; Llewellyn, Theo ; Downes, Elizabeth ; Oddy, Joseph ; MacIntosh, Catriona …
Endophytic fungi, Musa, Banana, Seed banking, Fusarium, Crop wild relatives, and Seed mycobiome